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Lipid Chemistry and Metabolism MCQs
397 MCQs with clinical pearls · MBBS Biochemistry · Prof Jariya
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Topics covered (48)
- Fatty Acid Structure and Classification — 43 MCQs
- Cholesterol Synthesis and Regulation — 27 MCQs
- Eicosanoids — 21 MCQs
- Lipoproteins and Atherosclerosis — 19 MCQs
- Bile Acid Metabolism — 16 MCQs
- Fatty Acid Synthesis Regulation — 16 MCQs
- Lipid Digestion and Absorption — 14 MCQs
- Nutritional Significance of Lipids — 13 MCQs
- Lipoproteins and Lipoprotein Disorders — 13 MCQs
- Ketone Body Metabolism — 12 MCQs
- Phospholipids — 11 MCQs
- Fatty Acid Synthesis — 11 MCQs
- Fatty Acid Oxidation — 11 MCQs
- Essential Fatty Acids — 10 MCQs
- Carnitine Shuttle — 10 MCQs
- Fatty Liver and Triglyceride Metabolism — 10 MCQs
- Lipid Storage Disorders — 9 MCQs
- Glycolipids and Gangliosides — 8 MCQs
- Sphingolipidoses — 8 MCQs
- Cholesterol — 7 MCQs
- Sphingolipids — 7 MCQs
- Lipid Peroxidation — 7 MCQs
- Lipoproteins — 6 MCQs
- MCAD Deficiency — 6 MCQs
- Lipoprotein Metabolism — 6 MCQs
- Lipid Classification — 5 MCQs
- Fatty Acid Nomenclature — 5 MCQs
- Zellweger Syndrome — 5 MCQs
- Surfactant and ARDS — 5 MCQs
- Fatty Acid Beta-Oxidation — 5 MCQs
- Membrane Lipids and Antioxidants — 5 MCQs
- Milky Plasma — 4 MCQs
- Lipolysis — 4 MCQs
- Reverse Cholesterol Transport — 4 MCQs
- Unsaturated Fatty Acid Beta-Oxidation — 3 MCQs
- Odd Chain Fatty Acid Beta-Oxidation — 3 MCQs
- Peroxisomal Beta-Oxidation — 3 MCQs
- Eicosanoid Metabolism — 3 MCQs
- Metabolic Syndrome — 3 MCQs
- NAFLD and NASH — 3 MCQs
- Diabetes and Lipid Metabolism — 3 MCQs
- Omega-3 and Omega-6 — 3 MCQs
- Triacylglycerol Synthesis — 2 MCQs
- Fatty Liver — 2 MCQs
- RDS — 2 MCQs
- Phospholipid Synthesis — 2 MCQs
- Reactive Oxygen Species — 1 MCQs
- Atherosclerosis — 1 MCQs
Sample MCQs with clinical pearls
Which of the following may be defined as esters of fatty acids with alcohol?
A) Compound lipids
B) Derived lipids
C) Phospholipids
D) Simple lipids ✔
E) Sphingolipids
SIMPLE LIPIDS are esters of fatty acids with an alcohol - FATS when the alcohol is glycerol, WAXES when it is a long-chain alcohol. COMPOUND lipids contain an additional group: phospholipids, glycolipids and lipoproteins. DERIVED lipids are the products of hydrolysis - fatty acids, glycerol, steroids, fatty aldehydes and ketone bodies. MEMORY: 'Simple is fatty acid plus alcohol and nothing else.'
Which of the following best describes tripalmitin?
A) Compound lipid
B) Mixed triacylglycerol
C) Phospholipid
D) Simple lipid
E) Simple triacylglycerol ✔
TRIPALMITIN is a SIMPLE triacylglycerol, carrying three identical palmitic acid residues. A MIXED triacylglycerol carries two or three different fatty acids, which is what almost all natural fats are - so simple triacylglycerols are largely a teaching construct. MEMORY: 'Same fatty acid three times makes it simple; different ones make it mixed.'
Which of the following is the glycerophospholipid in which the fatty acid at carbon 1 is replaced by an unsaturated alkyl group?
A) Cardiolipin
B) Lecithin
C) Plasmalogen ✔
D) Platelet activating factor
E) Sphingomyelin
PLASMALOGENS have the carbon-1 fatty acid attached by an ETHER rather than an ester bond, with a vinyl ether double bond. They form about 20% of membrane phospholipids and are abundant in myelin, heart and skeletal muscle. They are synthesised in PEROXISOMES, which is why plasmalogen deficiency is a feature of ZELLWEGER syndrome and rhizomelic chondrodysplasia punctata. MEMORY: 'Ether at carbon 1, and made in the peroxisome.'
These are three of 397 MCQs in this section. Every question carries a clinical pearl explaining the reasoning.
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