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6. Lipids and Fatty Acids — Biochemistry MCQs
KEMU · 161 MCQs with clinical pearls · Prof Jariya
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Sections in this kemu
- Fatty Acid Structure and Classification — 43 MCQs
- Eicosanoids — 21 MCQs
- Bile Acid Metabolism — 16 MCQs
- Nutritional Significance of Lipids — 13 MCQs
- Phospholipids — 11 MCQs
- Essential Fatty Acids — 10 MCQs
- Glycolipids and Gangliosides — 8 MCQs
- Cholesterol — 7 MCQs
- Sphingolipids — 7 MCQs
- Lipid Peroxidation — 7 MCQs
- Lipid Classification — 5 MCQs
- Fatty Acid Nomenclature — 5 MCQs
- Eicosanoid Metabolism — 3 MCQs
- Omega-3 and Omega-6 — 3 MCQs
Sample MCQs with clinical pearls
Which of the following may be defined as esters of fatty acids with alcohol?
A) Compound lipids
B) Derived lipids
C) Phospholipids
D) Simple lipids ✔
E) Sphingolipids
SIMPLE LIPIDS are esters of fatty acids with an alcohol - FATS when the alcohol is glycerol, WAXES when it is a long-chain alcohol. COMPOUND lipids contain an additional group: phospholipids, glycolipids and lipoproteins. DERIVED lipids are the products of hydrolysis - fatty acids, glycerol, steroids, fatty aldehydes and ketone bodies. MEMORY: 'Simple is fatty acid plus alcohol and nothing else.'
Which of the following best describes tripalmitin?
A) Compound lipid
B) Mixed triacylglycerol
C) Phospholipid
D) Simple lipid
E) Simple triacylglycerol ✔
TRIPALMITIN is a SIMPLE triacylglycerol, carrying three identical palmitic acid residues. A MIXED triacylglycerol carries two or three different fatty acids, which is what almost all natural fats are - so simple triacylglycerols are largely a teaching construct. MEMORY: 'Same fatty acid three times makes it simple; different ones make it mixed.'
Which of the following is the glycerophospholipid in which the fatty acid at carbon 1 is replaced by an unsaturated alkyl group?
A) Cardiolipin
B) Lecithin
C) Plasmalogen ✔
D) Platelet activating factor
E) Sphingomyelin
PLASMALOGENS have the carbon-1 fatty acid attached by an ETHER rather than an ester bond, with a vinyl ether double bond. They form about 20% of membrane phospholipids and are abundant in myelin, heart and skeletal muscle. They are synthesised in PEROXISOMES, which is why plasmalogen deficiency is a feature of ZELLWEGER syndrome and rhizomelic chondrodysplasia punctata. MEMORY: 'Ether at carbon 1, and made in the peroxisome.'
161 MCQs are arranged to the learning outcomes of this kemu.
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